Histomer Formula 301 Skin Clear Day & Night Drops Kit
A complete clinical routine for oily, acne-prone, and impure skin — built around Histomer’s proprietary Formula 301 skin renewal system. Two targeted serums work in sequence: one purifies and repairs overnight, the other controls sebum and shields skin through the day. Italian dermatological formulation, designed for visible results within weeks.
What’s in the kit
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Skin Clear Night Drops — An acid-based purifying serum applied before bed. Works overnight to exfoliate dead cells, decongest pores, calm inflammation, and accelerate skin renewal. Contains lactobionic and shikimic acids (SRF complex), madecassoside (Calmokyne), and centella meristem cells.
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Skin Clear Day Drops SPF20 — A lightweight daytime serum that regulates sebum production, minimizes shine, and provides broad-spectrum UV protection. Applies cleanly under makeup. Contains baobab and stogolovnik extracts, decylene glycol, and piroctone olamine to control surface bacteria.
Key actives and what they do
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SRF Complex (Lactobionic + Shikimic Acids) — Gentle chemical exfoliation that resurfaces without stripping. Improves texture, reduces post-acne marks, and refines enlarged pores.
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Calmokyne (Madecassoside) — Derived from centella asiatica. Calms redness and inflammation associated with active breakouts.
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Centella Meristem Cells — Supports skin repair and barrier recovery after acid treatment.
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Piroctone Olamine + Decylene Glycol — Antimicrobial actives that reduce acne-causing bacteria on the skin surface.
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SPF20 UV Filters — Essential protection during acid use, when skin is more photosensitive.
What to expect
In the first week: skin may feel slightly more sensitive as the acids begin working — this is normal. By week two to three: visible reduction in shine, fewer active breakouts, and smoother texture. By week four: pores appear tighter, skin tone more even, and post-acne marks begin to fade. SPF20 in the day serum is not optional — acid use without UV protection will worsen pigmentation.
How to use
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Night: Apply Skin Clear Night Drops to clean, dry skin with a cotton pad. Avoid the eye area. Leave overnight. Do not layer with other acids.
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Day: Apply Skin Clear Day Drops SPF20 to clean skin each morning. Massage gently until absorbed. Can be worn under makeup.
Who it is for
- Oily, combination, and acne-prone skin types
- Skin with enlarged pores, blackheads, or recurring breakouts
- Post-acne hyperpigmentation and uneven texture
- Anyone starting a clinical acid routine for the first time
Who it is not for
- Dry or very sensitive skin — the acid complex may be too active
- Anyone currently using retinoids — do not combine without professional guidance
- Pregnant or breastfeeding — consult a dermatologist before use