{"product_id":"histomer-hisiris-night-repair-dermal-cream","title":"Histomer Hisiris Night Repair Dermal Cream – Overnight Renewal for Sensitive Skin","description":"\u003ch2\u003eHistomer Hisiris Night Repair Dermal Cream – Overnight Renewal for Sensitive Skin\u003c\/h2\u003e\n\u003cp\u003eA rich overnight repair cream from \u003cstrong\u003eHistomer,\u003c\/strong\u003e the Italian clinical skincare brand. Part of the \u003cstrong\u003eHisiris Pro Dermis\u003c\/strong\u003e line, formulated for constitutionally sensitive skin prone to irritation, allergies, and reactivity. Works during sleep, when the skin’s natural repair processes are most active, to strengthen the skin barrier, reduce redness and dryness, counteract wrinkles and dark spots, and improve skin resilience. By morning, skin feels calmer, more even, and visibly refreshed.\u003c\/p\u003e\n\u003ch3\u003eKey actives and what they do\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHisiris Complex (Proprietary Desensitizing Complex)\u003c\/strong\u003e — Histomer’s signature active across the Hisiris range. A blend of desensitizing and anti-inflammatory agents that reduce the skin’s reactivity threshold — making it less likely to react to environmental triggers, temperature changes, and topical products over time. With consistent use, the skin becomes progressively more resilient and less reactive.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBarrier-Strengthening Lipids\u003c\/strong\u003e — Sensitive skin typically has a compromised skin barrier — the protective outer layer that prevents moisture loss and blocks irritants. The cream’s lipid complex replenishes the barrier’s structural components (ceramides, fatty acids) overnight, reducing transepidermal water loss and improving the skin’s ability to defend itself against daily stressors.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSoothing Botanical Actives\u003c\/strong\u003e — Anti-inflammatory plant extracts that calm redness, reduce irritation, and support the skin’s natural healing response during sleep. Particularly effective for skin that ends the day feeling tight, inflamed, or reactive after environmental exposure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Renewal Actives\u003c\/strong\u003e — Support the skin’s natural overnight cell turnover process. Improve skin tone evenness, counteract the appearance of dark spots, and progressively smooth fine lines with consistent nightly use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDeep Hydration Complex\u003c\/strong\u003e — A combination of humectants and emollients that restore moisture levels overnight. Sensitive skin loses moisture more rapidly than normal skin due to barrier compromise — the overnight hydration complex ensures skin wakes up plump and comfortable rather than tight and dry.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy nighttime application matters\u003c\/h3\u003e\n\u003cp\u003eSkin cell renewal peaks between 11pm and 4am. During sleep, the skin’s repair mechanisms are most active, blood flow to the skin increases, and the skin is not exposed to UV, pollution, or environmental stressors. A rich, active overnight cream applied at this time delivers ingredients when the skin is most receptive — and without the competition of SPF or makeup layered on top. For sensitive skin that spends the day defending itself against triggers, nighttime is the primary window for genuine repair.\u003c\/p\u003e\n\u003ch3\u003eWhat to expect\u003c\/h3\u003e\n\u003cp\u003eImmediate: skin feels calmer and more comfortable after the first night. Redness and tightness are visibly reduced by morning. With consistent nightly use over 4–8 weeks: progressive strengthening of the skin barrier, reduced frequency and intensity of sensitivity reactions, improved skin tone evenness, and a more resilient, radiant complexion. The desensitizing effect builds over time — skin becomes less reactive with each week of consistent use.\u003c\/p\u003e\n\u003ch3\u003eWho it is for\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eConstitutionally sensitive skin prone to irritation, allergies, and reactivity (Hisiris Pro Dermis)\u003c\/li\u003e\n\u003cli\u003eSkin that feels tight, dry, red, or inflamed at the end of the day\u003c\/li\u003e\n\u003cli\u003eAnyone wanting to strengthen their skin barrier and reduce long-term sensitivity\u003c\/li\u003e\n\u003cli\u003eAll ages — sensitivity is not age-dependent\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWho it is not for\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSensitive vascular skin with redness, couperose, or rosacea — use Hisiris Pro Rose instead\u003c\/li\u003e\n\u003cli\u003eMature sensitive skin with dryness, fragility, and loss of tone — use Hisiris Pro Age instead\u003c\/li\u003e\n\u003cli\u003eAnyone looking for a lightweight gel or fluid night treatment — this is a rich cream emulsion\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eAbout the Hisiris line\u003c\/h3\u003e\n\u003cp\u003eThe Hisiris range by Histomer addresses different forms of skin sensitivity with three targeted sub-lines. \u003cstrong\u003ePro Dermis\u003c\/strong\u003e is for constitutionally sensitive skin prone to irritation and allergies. \u003cstrong\u003ePro Rose\u003c\/strong\u003e is for sensitive vascular skin with redness, couperose, or rosacea. \u003cstrong\u003ePro Age\u003c\/strong\u003e is for mature skin prone to dryness, fragility, and loss of tone. Each sub-line uses the same Hisiris desensitizing complex as its foundation, with additional actives tailored to the specific sensitivity type.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eClinical skincare by Histomer. Made in Italy. Dermatologically tested. For external use only. Avoid contact with eyes.\u003c\/em\u003e\u003c\/p\u003e","brand":"Histomer","offers":[{"title":"Default Title","offer_id":32282995720226,"sku":"ET1000000173","price":363.0,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0253\/9405\/3154\/files\/hisiris_night_repair_dermal_cream_e11store.jpg?v=1773042193","url":"https:\/\/e11store.com\/products\/histomer-hisiris-night-repair-dermal-cream","provider":"E11 Store","version":"1.0","type":"link"}